Paul and Barnabas parted company because of a disagreement they had about John Mark. The young man had left their company and returned to Jerusalem. Barnabas wanted  to give John Mark, his nephew, another chance, but Paul preferred not to take him on this next trip. So Barnabas and John Mark went one way, and Paul chose Silas to accompany him on this trip. 

Besides Paul and Silas, there were two more preachers on the journey. A young Christian named Timothy joined them and so did Luke, the physician (who is the author of the book of Luke and the book of Acts). 

In Philippi, Paul meets Lydia, a wealthy businesswoman, and stays at her house. He also heals a fortune-telling slave girl whose owners have Paul and Silas arrested and thrown in jail. While in prison, there is an earthquake and their chains fall off. The jailer is converted when he hears Paul’s preaching about Jesus. 

They arrived in Thessalonica which was a seaport town. Paul preached for many weeks. Many Jews and Greeks believed his teaching, but Jewish leaders were once again alarmed at his teachings. Paul and Silas had to leave the city under the cover of darkness. 

Paul, Silas, and Timothy go to Berea and people listened to their stories of the teachings of Jesus. But once again, Paul is very close to be being arrested for his preaching. Paul flees to Athens, Greece, but  Silas and Timothy stay in Berea and intend to join Paul as soon as possible. 

When Paul arrives in Athens, he sees an altar to an unknown god and preaches about God to the Greeks. Many of them become believers. He continues on to Corinth, where Paul meets Aquilla and Priscilla, who join him in preaching the good news of Jesus. Paul writes 1 and 2 Thessalonians while staying in Corinth. 

After visiting a few more cities and churches, Paul returns to his home base of Antioch.